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单细胞RNA-Seq揭示了骨髓瘤肿瘤细胞的独特基因组
当细胞失去控制时,癌症就会出现。解读癌细胞的“蓝图” - 概述癌细胞如何劫持特定途径以实现不受控制的扩散 - 将导致更有效的方法来对抗它。来自魏...
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RNA-Seq揭示了人类基因组中小RNA表达的程度
虽然小的非编码RNA测序数据的数量不断增加,但仍然不清楚小RNA在人类基因组中的代表程度。萨尔大学的研究人员已经分析了来自近25,000个数据集的3030亿个...
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RNA-Seq reveals the extent of small RNAs representation in t
While the amount of small non-coding RNA sequencing data is continuously increasing, it is still unclear to which extent small RNAs are represented in the human genome. Saarland University researchers ...
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单细胞测序揭示了癌症在特定细胞类型中形成的
 虽然我们体内的许多细胞可以积累致癌突变,但这些事件中的大多数不会导致肿瘤形成,因为这些异常细胞被防御机制消除。相反,当突变发生在对其特...
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Single cell sequencing sheds light on why cancers form in sp
While many cells in our bodies can accumulate oncogenic mutations, the majority of these events do not lead to tumor formation as these abnormal cells are eliminated by defense mechanisms. Instead, tum...
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单细胞RNA测序方法的比较分析
单细胞mRNA测序(scRNA-seq)允许分析异质细胞群,提供解决各种生物和医学问题的令人兴奋的可能性。最近开发了一系列方法,因此有必要系统地比较它们的灵...
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Comparative analysis of single-cell RNA-sequencing methods
Single-cell mRNA sequencing (scRNA-seq) allows to profile heterogeneous cell populations, offering exciting possibilities to tackle a variety of biological and medical questions. A range of methods has...
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